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Tuesday, May 29, 2018

LIST OF PASSERS AND TOP 10 PLACERS May 2018 CPA Certified Public Accountant Board Exam Result


The Professional Regulation Commission (PRC) and the Board of Accountancy announces the 2,843 out of 9,830 passers of May 2018 CPA Certified Public Accountant Board Exam Result . Held in Manila, Baguio, Cagayan de Oro, Cebu, Davao, Iloilo, Legaspi and Tacloban last May 13, 20 and 21, 2018. The result is expected in five (5) working days from the last day of examination.


EXAM COVERAGE
May 13, 2018
1. Auditing
2. Management Advisory Services

May 20, 2018
1. Taxation
2. Regulatory Framework for Business Transaction

May 21, 2018
1. Financial Accounting and Reporting
2. Advanced Financial Accounting and Reporting



LIST OF TOP 10 PLACERS
May 2018 CPA Certified Public Accountant Board Exam Result

1 JAYSON ONG CHAN SAINT PAUL SCHOOL OF
PROFESSIONAL STUDIES - PALO 92.50

2 JOMARI JESS SACENDONCILLO ABELLAR SAINT PAUL SCHOOL OF
PROFESSIONAL STUDIES - PALO 91.67

3 EDDIELYN ABASOLA MORFE ISABELA STATE UNIVERSITYECHAGUE
91.00

STEWART HERBIE TAN PO UNIVERSITY OF SAN CARLOS 91.00

4 ERRA KAYE HERUELA DOBLE UNIVERSITY OF SAN CARLOS 90.83

5 MARK JASON POLVITO ABARCA FAR EASTERN UNIVERSITY-MANILA 90.67

6 ROBERT CARL ANGELO BALTAZAR ARROJO DE LA SALLE UNIVERSITY-MANILA 90.50

CHRISTINE JOY CABRAL JACINTO UNIVERSITY OF THE PHILIPPINESDILIMAN
90.50

7 PELIZA FAITH DACUYAN CABAÑERO UNIVERSITY OF SAN CARLOS 89.83

IRISH ABELLA KABINGUE UNIVERSITY OF SAN CARLOS 89.83

DONALD MARK MARCOS RAPINAN UNIVERSITY OF THE CORDILLERAS
(for.BAGUIO C.F.) 89.83

JAPETH ZAMORA RUEDA SAN BEDA COLLEGE OF
ALABANG,INC.(ST.BENEDICT COLL) 89.83

8 CHARISSE MICHAELA JUNE QUILICOT CATIEL UNIVERSITY OF SAN CARLOS 89.50

PRINCESS OBREGON GUMANIT UNIVERSITY OF SAN JOSERECOLETOS
89.50

MIGUEL ALBERT MORANTTE TAVEROS UNIVERSITY OF SAN CARLOS 89.50

9 FRITZ AMIEL LAMIS DESABILLE SOUTHWESTERN UNIVERSITY 89.33

ANGELA JOY TIU GO UNIVERSITY OF SAN CARLOS 89.33

RICHMOND JOHN TIU ROCKWELL UNIVERSITY OF SAN CARLOS 89.33

10 MA LUCILLE VELASCO FERRER UNIVERSITY OF SAN JOSERECOLETOS
89.17

MONIQUE THERESE PUA MUJER DE LA SALLE UNIVERSITY-MANILA 89.17





LIST OF PASSERS AND TOP 10 PLACERS
May 2018 CPA Certified Public Accountant Board Exam Result

See the Complete  LIST of PASSERS LINK/SOURCE: 

https://prcexamsresult.blogspot.com/

Tuesday, May 22, 2018

Nipah virus (NiV) Transmission, Symptoms,Treatment,Risk of exposure and Prevention

Nipah virus (NiV) is a member of the family Paramyxoviridae, genus Henipavirus. NiV was initially isolated and identified in 1999 during an outbreak of encephalitis and respiratory illness among pig farmers and people with close contact with pigs in Malaysia and Singapore. Its name originated from Sungai Nipah, a village in the Malaysian Peninsula where pig farmers became ill with encephalitis. Given the relatedness of NiV to Hendra virus, bat species were quickly singled out for investigation and flying foxes of the genus Pteropus were subsequently identified as the reservoir for NiV (Distribution Map).
In the 1999 outbreak, Nipah virus caused a relatively mild disease in pigs, but nearly 300 human cases with over 100 deaths were reported. In order to stop the outbreak, more than a million pigs were euthanized, causing tremendous trade loss for Malaysia. Since this outbreak, no subsequent cases (in neither swine nor human) have been reported in either Malaysia or Singapore.
In 2001, NiV was again identified as the causative agent in an outbreak of human disease occurring in Bangladesh. Genetic sequencing confirmed this virus as Nipah virus, but a strain different from the one identified in 1999. In the same year, another outbreak was identified retrospectively in Siliguri, India with reports of person-to-person transmission in hospital settings (nosocomial transmission). Unlike the Malaysian NiV outbreak, outbreaks occur almost annually in Bangladesh and have been reported several times in India.

Transmission
Transmission of Nipah virus to humans may occur after direct contact with infected bats, infected pigs, or from other NiV infected people.
In Malaysia and Singapore, humans were apparently infected with Nipah virus only through close contact with infected pigs. The NiV strain identified in this outbreak appeared to have been transmitted initially from bats to pigs, with subsequent spread within pig populations. Incidental human infections resulted after exposure to infected pigs. No occurrence of person-to-person transmission was reported in this outbreak.
Conversely, person-to-person transmission of Nipah virus in Bangladesh and India is regularly reported. This is most commonly seen in the family and caregivers of Nipah virus-infected patients. Transmission also occurs from direct exposure to infected bats. A common example is consumption of raw date palm sap contaminated with infectious bat excretions.

Diagnosis
Laboratory diagnosis of a patient with a clinical history of NiV can be made during the acute and convalescent phases of the disease by using a combination of tests. Virus isolation attempts and real time polymerase chain reaction (RT-PCR) from throat and nasal swabs, cerebrospinal fluid, urine, and blood should be performed in the early stages of disease. Antibody detection by ELISA (IgG and IgM) can be used later on. In fatal cases, immunohistochemistry on tissues collected during autopsy may be the only way to confirm a diagnosis.

Signs and Symptoms
Infection with Nipah virus is associated with encephalitis (inflammation of the brain). After exposure and an incubation period of 5 to 14 days,illness presents with 3-14 days of fever and headache, followed by drowsiness, disorientation and mental confusion. These signs and symptoms can progress to coma within 24-48 hours. Some patients have a respiratory illness during the early part of their infections, and half of the patients showing severe neurological signs showed also pulmonary signs.
During the Nipah virus disease outbreak in 1998-99, 265 patients were infected with the virus. About 40% of those patients who entered hospitals with serious nervous disease died from the illness.
Long-term sequelae following Nipah virus infection have been noted, including persistent convulsions and personality changes.
Latent infections with subsequent reactivation of Nipah virus and death have also been reported months and even years after exposure.

Treatment
Treatment is limited to supportive care. Because Nipah virus encephalitis can be transmitted person-to-person, standard infection control practices and proper barrier nursing techniques are important in preventing hospital-acquired infections (nosocomial transmission).
The drug ribavirin has been shown to be effective against the viruses in vitro, but human investigations to date have been inconclusive and the clinical usefulness of ribavirin remains uncertain.
Passive immunization using a human monoclonal antibody targeting the Nipah G glycoprotein has been evaluated in the post-exposure therapy in the ferret model and found to be of benefit.

Risk of exposure
clay pot with raw date palm sap inside, credit to Ilana Schafer
cdc,com
In the Malaysia and Singapore outbreak, Nipah virus infection was associated with close contact with Nipah virus-infected pigs.
In Bangladesh and India, where Nipah virus infection is more frequent, exposure has been linked to consumption of raw date palm sap and contact with bats. Importantly, human-to-human transmission has been documented and exposure to other Nipah virus infected individuals is also a risk factor.

Prevention
Nipah virus infection can be prevented by avoiding exposure to sick pigs and bats in endemic areas and not drinking raw date palm sap.
Additional efforts focused on surveillance and awareness will help prevent future outbreaks. Research is needed to better understand the ecology of bats and Nipah virus, investigating questions such as the seasonality of disease within reproductive cycles of bats. Surveillance tools should include reliable laboratory assays for early detection of disease in communities and livestock, and raising awareness of transmission and symptoms is important in reinforcing standard infection control practices to avoid human-to-human infections in hospital settings (nosocomial infection).
A subunit vaccine, using the Hendra G protein, produces cross-protective antibodies against HENV and NIPV has been recently used in Australia to protect horses against Hendra virus. This vaccine offers great potential for henipavirus protection in humans as well.
credit/sources: 
1.  https://www.cdc.gov/vhf/nipah/index.html
2. ://www.cdc.gov/vhf/nipah/diagnosis/index.html
3. https://www.cdc.gov/vhf/nipah/symptoms/index.html
4. https://www.cdc.gov/vhf/nipah/symptoms/index.html
5. https://www.cdc.gov/vhf/nipah/exposure/index.html
6. https://www.cdc.gov/vhf/nipah/prevention/index.html


The (not so Scientific) Anatomy of a Cat


credit/source: facebook.com and Buzzfeed Animals

Friday, May 18, 2018

Loss vs. Lost: What’s the Difference?

Both loss and lost have to do with losing. To lose something is to misplace it, to fail to win, to get rid of, or a number of other meanings.
  • To misplace something.
    • He keeps losing his car keys.
  • To fail to win.
    • The Lakers are losing the game right now.
  • To rid oneself of.
    • I will be losing 10 pounds this year.
Although loss and lost both deal with the same subject, they perform different functions in a sentence.

What is the Difference Between Loss and Lost?

After reading this post, you won’t ever again wonder, “When do I use lost or loss?”

When to Use Loss

loss versus lost grammarWhat does loss mean? Loss is a noun and is defined as the act or an instance of losing.
  • That was an unexpected loss.
  • The family suffered a terrible loss with the death of Jane.
If you sell something at a loss, you are selling it below cost.

When to Use Lost

lost versus loss meaningWhat does lost mean? Lost is the past tense and past participle of lose. Since lost is a verb, you should expect to see it following a subject of some kind.
  • She lost her car in the crowded parking lot.
Lost as an adjectiveLost can also function as an adjective in a sentence.
  • The lost child.
  • A lost opportunity.
  • My basketball is lost

Examples

  • Angels center fielder Mike Trout brought comfort — and gifts — to a South New Jersey family that lost its home to a fire with a surprise Christmas Eve visit. –L.A. Times
  • Before the season, the Vikings lost two of their top players. –The Washington Post
  • The Japanese conglomerate has been struggling with the aftermath of a major accounting scandal, compounded by troubles in nuclear energy and losses in the business that makes personal computers, TVs and consumer appliances. –Houston Chronicle

Trick to Remember the Difference

Here is a good trick to remember lost vs. loss. If you can remember this simple mental check, you will be all set.
Check one: Lost is the past tense of to lose. Lost and past tense both contain the letter “t.”

Summary

Is it lost or loss? Both words have to do with losing something, but they are different parts of speech.
Loss is a noun and refers to the act of losing.
Lost is the past tense and past participle of to lose.
credit/source: https://writingexplained.org/loss-vs-lost-difference

Thursday, May 17, 2018

Marc Spelmann gets the first Golden Buzzer of 2018 | Auditions Week 1 | ...


credit/source: youtube.com and Britain's Got Talent 2018 ft. Marc Spellmann

I had written and posted a poem on March 18, 2018 that I can describe related or a little bit similarly entitled Between Life, Death and Faith and it goes like this.

Our purpose in Life begins with our Birth, reason why we live and

Ends it on our Death, our mission has been accomplished.

Nothing in this world is pure coincidence even with our own free will.

Each and everyone is either in perpendicular line or parallel.We meet in our crossed roads.

But remember,Faith can move mountain.


Wednesday, May 9, 2018

Ménière’s disease Causes,Symptoms,Diagnosis and Treatment,

WHAT IS MÉNIÈRE'S DISEASE?
Ménière's disease describes a set of episodic symptoms including vertigo (attacks of a spinning sensation), hearing loss, tinnitus (a roaring, buzzing, or ringing sound in the ear), and a sensation of fullness in the affected ear. Episodes typically last from 20 minutes up to 4 hours. Hearing loss is often intermittent, occurring mainly at the time of the attacks of vertigo. Loud sounds may seem distorted and cause discomfort. Usually, the hearing loss involves mainly the lower pitches, but over time this often affects tones of all pitches. After months or years of the disease, hearing loss often becomes permanent. Tinnitus and fullness of the ear may come and go with changes in hearing, occur during or just before attacks, or be constant.

Ménière’s disease is also called idiopathic endolymphatic hydrops and is one of the most common causes of dizziness originating in the inner ear.  In most cases only one ear is involved, but both ears may be affected in about 15 percent of patients. Ménière’s disease typically starts between the ages of 20 and 50 years. Men and women are affected in equal numbers.  Because Ménière’s disease affects each person differently, your doctor will suggest strategies to help reduce your symptoms and will help you choose the treatment that is best for you.
WHAT ARE THE CAUSES?
Although the cause is unknown, Meniere's disease probably results from an abnormality in the volume of fluid in the inner ear. Too much fluid may accumulate either due to excess production or inadequate absorption.  In some individuals, especially those with involvement of both ears, allergies or autoimmune disorders may play a role in producing Ménière’s disease.  In some cases, other conditions may cause symptoms similar to those of Ménière’s disease.

People with Ménière's disease have a “sick” inner ear and are more sensitive to factors, such as fatigue and stress, that may influence the frequency of attacks.
HOW IS A DIAGNOSIS MADE?
Your physician will take a history of the frequency, duration, severity, and character of your attacks, the duration of hearing loss or whether it has been changing, and whether you have had tinnitus or fullness in either or both ears. When the history has been completed, diagnostic tests will check your hearing and balance functions. They may include:
For hearing
  • •An audiometric examination (hearing test) typically indicates a sensory type of hearing loss in the affected ear. Speech discrimination (the patient’s ability to distinguish between words like “sit” and “fit”) is often diminished in the affected ear.
 
For balance
  • •An ENG (electronystagmogram) may be performed to evaluate balance function. In a darkened room, eye movements are recorded as warm and cool water or air are gently introduced into each ear canal. Since the eyes and ears work in coordination through the nervous system, measurement of eye movements can be used to test the balance system. In about 50 percent of patients, the balance function is reduced in the affected ear.
  • Rotational or balance platform testing, may also be performed to evaluate the balance system.

Other tests
  • •Electrocochleography (ECoG) may indicate increased inner ear fluid pressure in some cases of Ménière’s disease.
  • The auditory brain stem response (ABR), a computerized test of the hearing nerves and brain pathways, computed tomography (CT), or magnetic resonance imaging (MRI) may be needed to rule out a tumor occurring on the hearing and balance nerve. Such tumors are rare, but they can cause symptoms similar to Ménière’s disease.

WHAT SHOULD I DO DURING AN ATTACK OF  MÉNIÈRE’S DISEASE?
Lie flat and still and focus on an unmoving object. Often people fall asleep while lying down and feel better when they awaken.
HOW CAN I REDUCE THE FREQUENCY OF MÉNIÈRE’S DISEASE EPISODES?
Avoid stress and excess salt ingestion, caffeine, smoking, and alcohol. Get regular sleep and eat properly. Remain physically active, but avoid excessive fatigue. Consult your otolaryngologist about other treatment options. 
HOW IS MÉNIÈRE’S DISEASE TREATED?
Although there is no cure for Ménière’s disease, the attacks of vertigo can be controlled in nearly all cases.  Treatment may include:
  • •A low salt diet and a diuretic (water pill)
  • •Anti-vertigo medications
  • •Intratympanic injection with either gentamicin or dexamethasone.
  • •An air pressure pulse generator
  • •Surgery
Your otolaryngologist will help you choose the treatment that is best for you, as each has advantages and drawbacks. In many people, careful control of salt in the diet and the use of diuretics can control symptoms satisfactorily.
 
Intratympanic injections involve injecting medication through the eardrum into the middle ear space where the ear bones reside. This treatment is done in the otolaryngologist’s office. The treatment includes either making a temporary opening in the eardrum or placing a tube in the eardrum. The drug may be administered once or several times. Medication injected may include gentamicin or corticosteroids. Gentamicin alleviates dizziness but also carries the possibility of increased hearing loss in the treated ear that may occur in some individuals. Corticosteroids do not cause worsening of hearing loss, but are less effective in alleviating the major dizzy spells.
 
An air pressure pulse generatoris another option. This device is a mechanical pump that is applied to the person’s ear canal for five minutes three times a day. A ventilating tube must be first inserted through the eardrum to allow the pressure produced by the air pressure pulse generator to be transmitted across the round window membrane and change the pressure in the inner ear. The success rate of this device has been variable.
WHEN IS SURGERY RECOMMENDED?
Surgery is needed in only a small minority of patients with Meniere’s disease. If vertigo attacks are not controlled by conservative measures and are disabling, one of the following surgical procedures might be recommended:
  • •Endolymphatic sac shunt or decompression procedure relieves attacks of vertigo in one-half to two-thirds of cases and the sensation of ear fullness is often improved. Control is often temporary. Endolymphatic sac surgery does not improve hearing, but only has a small risk of worsening it. Recovery time after this procedure is short compared to the other procedures.
  • •Selective vestibular neurectomy is a procedure in which the balance nerve is cut as it leaves the inner ear and goes to the brain. While vertigo attacks are permanently cured in a high percentage of cases, patients may continue to experience imbalance. Similar to endolymphatic sac procedures, hearing function is usually preserved.
  • •Labryrinthectomy and eighth nerve section are procedures in which the balance and hearing mechanism in the inner ear are destroyed on one side. This is considered when the patient with Ménière’s disease has poor hearing in the affected ear. Labryrinthectomy and eighth nerve section result in the highest rates for control of vertigo attacks.
  • credit/source: http://www.entnet.org/content/menieres-disease
  • Note: All information are credited to the original writer's source and references. 

Ménière’s disease Causes,Symptoms,Diagnosis and Treatment,

What is Ménière’s disease?

Ménière’s disease is a disorder of the inner ear that causes severe dizziness (vertigo), ringing in the ears (tinnitus), hearing loss, and a feeling of fullness or congestion in the ear. Ménière’s disease usually affects only one ear.
Attacks of dizziness may come on suddenly or after a short period of tinnitus or muffled hearing. Some people will have single attacks of dizziness separated by long periods of time. Others may experience many attacks closer together over a number of days. Some people with Ménière’s disease have vertigo so extreme that they lose their balance and fall. These episodes are called “drop attacks.”
Ménière’s disease can develop at any age, but it is more likely to happen to adults between 40 and 60 years of age. The National Institute on Deafness and Other Communication Disorders (NIDCD) estimates that approximately 615,000 individuals in the United States are currently diagnosed with Ménière’s disease and that 45,500 cases are newly diagnosed each year.

What causes the symptoms of Ménière’s disease?

 The labyrinth in relation to the ear

The labyrinth in relation to the ear

The labyrinth is composed of the semicircular canals, the otolithic organs (i.e., utricle and saccule), and the cochlea. Inside their walls (bony labyrinth) are thin, pliable tubes and sacs (membranous labyrinth) filled with endolymph.
Credit: NIH/NIDCD
The symptoms of Ménière’s disease are caused by the buildup of fluid in the compartments of the inner ear, called the labyrinth. The labyrinth contains the organs of balance (the semicircular canals and otolithic organs) and of hearing (the cochlea). It has two sections: the bony labyrinth and the membranous labyrinth. The membranous labyrinth is filled with a fluid called endolymph that, in the balance organs, stimulates receptors as the body moves. The receptors then send signals to the brain about the body’s position and movement. In the cochlea, fluid is compressed in response to sound vibrations, which stimulates sensory cells that send signals to the brain.
In Ménière’s disease, the endolymph buildup in the labyrinth interferes with the normal balance and hearing signals between the inner ear and the brain. This abnormality causes vertigo and other symptoms of Ménière’s disease.

Why do people get Ménière’s disease?

Many theories exist about what happens to cause Ménière’s disease, but no definite answers are available. Some researchers think that Ménière’s disease is the result of constrictions in blood vessels similar to those that cause migraine headaches. Others think Ménière’s disease could be a consequence of viral infections, allergies, or autoimmune reactions. Because Ménière’s disease appears to run in families, it could also be the result of genetic variations that cause abnormalities in the volume or regulation of endolymph fluid.

How does a doctor diagnose Ménière’s disease?

Ménière’s disease is most often diagnosed and treated by an otolaryngologist (commonly called an ear, nose, and throat doctor, or ENT). However, there is no definitive test or single symptom that a doctor can use to make the diagnosis. Diagnosis is based upon your medical history and the presence of:
  • Two or more episodes of vertigo lasting at least 20 minutes each
  • Tinnitus
  • Temporary hearing loss
  • A feeling of fullness in the ear
Some doctors will perform a hearing test to establish the extent of hearing loss caused by Ménière’s disease. To rule out other diseases, a doctor also might request magnetic resonance imaging (MRI) or computed tomography (CT) scans of the brain.

How is Ménière’s disease treated?

Ménière’s disease does not have a cure yet, but your doctor might recommend some of the treatments below to help you cope with the condition.
  • Medications. The most disabling symptom of an attack of Ménière’s disease is dizziness. Prescription drugs such as meclizine, diazepam, glycopyrrolate, and lorazepam can help relieve dizziness and shorten the attack.
  • Salt restriction and diuretics. Limiting dietary salt and taking diuretics (water pills) help some people control dizziness by reducing the amount of fluid the body retains, which may help lower fluid volume and pressure in the inner ear.
  • Other dietary and behavioral changes. Some people claim that caffeine, chocolate, and alcohol make their symptoms worse and either avoid or limit them in their diet. Not smoking also may help lessen the symptoms.
  • Cognitive therapy. Cognitive therapy is a type of talk therapy that helps people focus on how they interpret and react to life experiences. Some people find that cognitive therapy helps them cope better with the unexpected nature of attacks and reduces their anxiety about future attacks.
  • Injections. Injecting the antibiotic gentamicin into the middle ear helps control vertigo but significantly raises the risk of hearing loss because gentamicin can damage the microscopic hair cells in the inner ear that help us hear. Some doctors inject a corticosteroid instead, which often helps reduce dizziness and has no risk of hearing loss.
  • Pressure pulse treatment. The U.S. Food and Drug Administration (FDA) recently approved a device for Ménière’s disease that fits into the outer ear and delivers intermittent air pressure pulses to the middle ear. The air pressure pulses appear to act on endolymph fluid to prevent dizziness.
    Meineres-Disease_Aug2010-fig2- Location of endolymphatic sac

    Location of endolymphatic sac

    Credit: NIH/NIDCD
  • Surgery. Surgery may be recommended when all other treatments have failed to relieve dizziness. Some surgical procedures are performed on the endolymphatic sac to decompress it. Another possible surgery is to cut the vestibular nerve, although this occurs less frequently.
  • Alternative medicine. Although scientists have studied the use of some alternative medical therapies in Ménière’s disease treatment, there is still no evidence to show the effectiveness of such therapies as acupuncture or acupressure, tai chi, or herbal supplements such as gingko biloba, niacin, or ginger root. Be sure to tell your doctor if you are using alternative therapies, since they sometimes can impact the effectiveness or safety of conventional medicines.

What is the outlook for someone with Ménière’s disease?

Scientists estimate that six out of 10 people either get better on their own or can control their vertigo with diet, drugs, or devices. However, a small group of people with Ménière’s disease will get relief only by undergoing surgery.

What research about Ménière’s disease is being done?

Insights into the biological mechanisms in the inner ear that cause Ménière’s disease will guide scientists as they develop preventive strategies and more effective treatment. The NIDCD is supporting scientific research across the country that is:
  • Determining the most effective dose of gentamicin with the least amount of risk for hearing loss.
  • Developing an in-ear device that uses a programmable microfluid pump (the size of a computer chip) to precisely deliver vertigo-relieving drugs to the inner ear.
  • Studying the relationship between endolymph volume and inner ear function to determine how much endolymph is “too much.” Researchers are hoping to develop methods for manipulating inner ear fluids and treatments that could lower endolymph volume and reduce or eliminate dizziness.

Where can I find additional information about Ménière’ disease?

NIDCD maintains a directory of organizations that can answer questions and provide printed or electronic information on Ménière’s. Please see the list of organizations at www.nidcd.nih.gov/directory.
credit/source: 

What is the outlook for someone with Ménière’s disease?

Scientists estimate that six out of 10 people either get better on their own or can control their vertigo with diet, drugs, or devices. However, a small group of people with Ménière’s disease will get relief only by undergoing surgery.

What research about Ménière’s disease is being done?

Insights into the biological mechanisms in the inner ear that cause Ménière’s disease will guide scientists as they develop preventive strategies and more effective treatment. The NIDCD is supporting scientific research across the country that is:
  • Determining the most effective dose of gentamicin with the least amount of risk for hearing loss.
  • Developing an in-ear device that uses a programmable microfluid pump (the size of a computer chip) to precisely deliver vertigo-relieving drugs to the inner ear.
  • Studying the relationship between endolymph volume and inner ear function to determine how much endolymph is “too much.” Researchers are hoping to develop methods for manipulating inner ear fluids and treatments that could lower endolymph volume and reduce or eliminate dizziness.

Where can I find additional information about Ménière’ disease?

NIDCD maintains a directory of organizations that can answer questions and provide printed or electronic information on Ménière’s. Please see the list of organizations at www.nidcd.nih.gov/directory.
credit/source:https://www.nidcd.nih.gov/health/menieres-disease
Note: All information and images are credited to the original writer's source and references














Monday, May 7, 2018

Dysentery Types,Causes,Symptoms,Treatment and Prevention

The Facts

Many people have spent a tropical vacation with a bad stomach bug.They might have had dysentery, a painful intestinal infection that is usually caused by bacteria or parasites. Dysentery is defined as diarrhea in which there is blood, pus, and mucous, usually accompanied by abdominal pain.
There are two main types of dysentery. The first type, amoebic dysenteryor intestinal amoebiasis, is caused by a single-celled, microscopic parasite living in the large bowel. The second type, bacillary dysentery, is caused by invasive bacteria. Both kinds of dysentery occur mostly in hot countries. Poor hygiene and sanitation increase the risk of dysentery by spreading the parasite or bacteria that cause it through food or water contaminated from infected human feces.

Causes

Dysentery can have a number of causes. Bacterial infections are by far the most common causes of dysentery. These infections include ShigellaCampylobacter, E. coli, and Salmonella species of bacteria. The frequency of each pathogen varies considerably in different regions of the world. For example, shigellosis is most common in Latin America while Campylobacter is the dominant bacteria in Southeast Asia. Dysentery is rarely caused by chemical irritants or by intestinal worms.
Intestinal amoebiasis is caused by a protozoan parasite, Entamoeba histolytica. The amoeba can exist for long periods of time in the large bowel (colon). In the vast majority of cases, amoebiasis causes no symptoms - only 10% of infected individuals become ill. It is uncommon except in the world's tropical zones, where it is very prevalent. People can become infected after ingesting feces that contain somebody's excreted parasites. People are at high risk of acquiring the parasite through food and water if the water for household use isn't separated from waste water. The parasites can also enter through the mouth when hands are washed in contaminated water. If people neglect to wash properly before preparing food, the food may become contaminated. Fruits and vegetables can be contaminated if washed in polluted water or grown in soil fertilized by human waste.
The Shigella and Campylobacter bacteria that cause bacillary dysentery are found all over the world. They penetrate the lining of the intestine, causing swelling, ulcerations, and severe diarrhea containing blood and pus. Both infections are spread by ingestion of feces within contaminated food and water. If people live or travel in an area where poverty or overcrowding may interfere with good hygiene and sanitation, they are at risk of being exposed to invasive bacteria. Young children (ages 1 to 4) living in poverty are most likely to contract shigellosiscampylobacteriosis, or salmonellosis.
Having sex that involves anal contact may spread amoebic and bacillary dysentery. 
This is especially true if the sex included direct anal or oral contact, or oral contact with an object (e.g., fingers) that touched or was in the anus of an infected person.

Symptoms and Complications

The main symptom of dysentery is frequent near-liquid diarrhea flecked with blood, mucus, or pus. Other symptoms include:
  • sudden onset of high fever and chills
  • abdominal pain
  • cramps and bloating
  • flatulence (passing gas)
  • urgency to pass stool
  • feeling of incomplete emptying
  • loss of appetite
  • weight loss
  • headache
  • fatigue
  • vomiting
  • dehydration
Other symptoms may be intermittent and may include recurring low fevers, abdominal cramps, increased gas, and milder and firmer diarrhea. You may feel weak and anemic, or lose weight over a prolonged period (emaciation). Mild cases of bacillary dysentery may last 4 to 8 days, while severe cases may last 3 to 6 weeks. Amoebiasis usually lasts about 2 weeks.
Bacillary dysentery symptoms begin within 2 to 10 days of infection. In children, the illness starts with fever, nausea, vomiting, abdominal cramps, and diarrhea. Episodes of diarrhea may increase to as much as once an hour with blood, mucus, and pus in the child's stool. Vomiting may result in rapid and severe dehydration, which may lead to shock and death if not treated. Signs of dehydration include an extremely dry mouth, sunken eyes, and poor skin tone. Children and infants will be thirsty, restless, irritable, and possibly lethargic. Children may also have sunken eyes and may not be able to produce tears or urine, the latter appearing very dark and concentrated.
Complications from bacillary dysentery include delirium, convulsions, and coma. A very severe infection like this can be fatal within 24 hours. However, the vast majority of infections are self-limited and resolve spontaneously without treatment.
People with amoebic dysentery may experience other problems associated with amoebiasis. The most frequent complication results when parasites spread to the liver, causing an amoebic abscess. In this case, you would have a high fever and experience weight loss and right shoulder or upper abdominal pain. If the infection of the bowel is especially virulent, the intestinal ulcerations may lead to bowel perforation and death. The parasites may rarely spread through the bloodstream, causing infection in the lungs, brain, and other organs.

Making the Diagnosis

If a doctor suspects dysentery, a stool sample usually will be required for analysis. For bacterial infections such as shigella, the diagnosis is made by culture of the stool. Unfortunately, such cultures are not available in most developing countries and the diagnosis is made clinically on the basis of symptoms. Amoebiasis is often diagnosed by finding parasites under a microscope. An antibody blood test helps to confirm the diagnosis of amoebic dysentery or liver abscess.
The E. histolytica has an identical "twin brother," Entamoeba dispar, a harmless amoeba that looks identical to E. histolytica under the microscope. It never produces symptoms and does not require treatment. In developing countries, the distinction is not usually made - individuals found to have amoebae in their stools are treated whether or not it is clear that the infection is causing symptoms. Of those diagnosed with amoebae in their stools, 90% have the harmless E. dispar.

Treatment and Prevention

Antiparasitic medications such as metronidazole* and iodoquinol, are commonly used to treat dysentery caused by amoebiasis.Antibiotics like ciprofloxacin, ofloxacin, levofloxacin, or azithromycin are used to treat the organisms causing bacillary dysentery. People with prolonged diarrhea should consult with their doctor. If you travel, you should carry a one- to three-day self-treatment antibiotic regimen such as ciprofloxacin and use it in the case of sudden moderate-to-severe diarrheal illness. Bismuth subsalicylate (Pepto-Bismol®) can also be helpful for some travelers. In addition, use the antidiarrheal medication loperamide to slow the bowel and prevent dehydration. Consult your doctor for children under 2 years of age.
It is most important to replace the fluids lost from diarrhea. In mild cases, soft drinks, juices, and bottled water will be enough. More severe diarrhea should be treated with solutions that contain electrolytes such as potassium, salt, and sucrose. For severe diarrhea, commercial oral rehydration solutions are usually needed. These solutions are available in packets for easy travel. People should try to consume enough fluids so that clear-to-light yellow urine is produced every 3 to 4 hours. While affected with dysentery, it is better to stick to a bland diet (bananas, rice, soda crackers) and avoid milk products.
Dysentery can be prevented to some extent by practising careful personal hygiene.
People who travel to or live in areas with high rates of dysentery should follow the following advice:
  • Always use a condom for any sexual activity involving anal contact and wash carefully before and after sexual activity.
  • Do not eat any foods cooked in unhygienic circumstances, such as from street vendors.
  • Only eat cooked foods that have been heated to a high temperature. Do not eat cooked foods that have cooled.
  • Do not eat raw vegetables. Avoid species of fruits without peels. Open fruits with peels yourself.
  • Drink only commercially bottled or boiled water. Do not use ice unless it has been made from purified water.
  • Use only bottled or boiled water to wash and to cook food in, to wash hands, and to brush teeth.
  • Consider traveling with an alcohol-based hand sanitizer.
  • credit/source: http://www.medbroadcast.com/condition/getcondition/dysentery
  • Note: all information are credited to the original writer's source and references.

Thursday, May 3, 2018

STD:Chlamydia on What need to know if get treated for chlamydia?

What is Chlamydia?

Chlamydia is a bacterial infection that’s easily cured with antibiotic medicine. It’s one of the most common STDs, and most people who have chlamydia don’t show any symptoms.

Chlamydia is really common.

Chlamydia is a SUPER common bacterial infection that you can get from sexual contact with another person. Close to 3 million Americans get it every year, most commonly among 14-24-year-olds.
Chlamydia is spread through vaginal, anal, and oral sex. The infection is carried in semen (cum), pre-cum, and vaginal fluids. Chlamydia can infect the penisvaginacervixanusurethra, eyes, and throat. Most people with chlamydia don’t have any symptoms and feel totally fine, so they might not even know they’re infected.
Chlamydia can be easily cleared up with antibiotics. But if you don’t treat chlamydia, it may lead to major health problems in the future. That’s why STD testing is so important — the sooner you know you have chlamydia, the faster you can cure it. You can prevent chlamydia by using condoms every time you have sex.

How do you get chlamydia?

Chlamydia is usually spread during sexual contact with someone who has the infection. It can happen even if no one cums. The main ways people get chlamydia are from having vaginal sex and anal sex, but it can also be spread through oral sex.
Rarely, you can get chlamydia by touching your eye if you have infected fluids on your hand. Chlamydia can also be spread to a baby during birth if the mother has it.
Chlamydia isn’t spread through casual contact, so you CAN’T get chlamydia from sharing food or drinks, kissing, hugging, holding hands, coughing, sneezing, or sitting on the toilet.
Using condoms and/or dental dams every time you have sex is the best way to help prevent chlamydia.

What’s the treatment for chlamydia?

Chlamydia is usually easy to get rid of. Your nurse or doctor will get you antibiotics to treat the infection. Sometimes you only have to take one dose of medication. Another chlamydia treatment lasts for 7 days. Your doctor will help you figure out which treatment is best for you.
If you’re treated for chlamydia, it’s really important for your sexual partners to get treated also. Otherwise, you can keep passing the infection back and forth, or to other people. Sometimes your doctor will give you medicine for both you and your partner.

What do I need to know if I get treated for chlamydia?

If you’re getting treated for chlamydia:
  • Take all of your medicine the way your doctor tells you to, even if the symptoms go away sooner. The infection stays in your body until you finish the antibiotics.
  • Your partner(s) should also get treated for chlamydia so you don’t re-infect each other or anyone else.
  • Don’t have sex for 7 days. If you only have 1 dose of medication, wait for 7 days after you take it before having sex. If you’re taking medicine for 7 days, don’t have sex until you’ve finished all of your pills.
  • Get tested again in 3-4 months to make sure your infection is gone.
  • Don’t share your medicine with anyone. Your doctor may give you a separate dose of antibiotics for your partner. Make sure you both take all of the medicine you get.
  • Even if you finish your treatment and the chlamydia is totally gone, it’s possible to get a new chlamydia infection again if you’re exposed in the future. Chlamydia isn’t a one-time-only deal. So use condoms and get tested regularly.

What happens if you don’t get treated for chlamydia?

Even though chlamydia is common and doesn’t always cause any symptoms, it can become a big deal if it’s not caught and treated early.
Chlamydia can spread to your uterus and fallopian tubes, causing pelvic inflammatory disease (PID). PID might not have any symptoms at first, but there can be permanent damage that leads to pain, infertility, or ectopic pregnancy. Getting tested for chlamydia really reduces your chances of getting PID.
If you have a penis, a chlamydia infection can spread to your epididymis(a tube that carries sperm from your testicles), and can cause chronic joint pain. Rarely, it can make you infertile.
Having chlamydia may increase your chances of getting or spreading HIV, the virus that causes AIDS.
If you have chlamydia during your pregnancy and don’t treat it, you can pass it to your baby when you’re giving birth. Chlamydia can cause eye infections and pneumonia in newborns, and it also increases the risk of delivering your baby too early. Testing and treatment for chlamydia is quick, easy, and the best way to avoid all these problems.
credit/source: https://www.plannedparenthood.org/learn/stds-hiv-safer-sex/chlamydia
Note: All information are credited to the original writer's source and references.